Biochemistry
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Temperature and pH effects on the formation of cyclodextrin-fluorouracil and cyclodextrin-uracil complexes.
(Wheaton College (MA)., 2018)This study analyses the effects of pH and temperature on cyclodextrin-fluorouracil and cyclodextrin-uracil complexes. Fluorouracil is a chemotherapy drug given in high dosages leading to severe adverse effects. To reduce ... -
Zebrafish aging is a determining factor in breast cancer cell xenotransplant efficacy.
(Wheaton College (Norton, Mass.), 2017)Breast cancer is the most commonly diagnosed cancer in women and a leading cause of cancer death in women. Studies that examine the effects of certain environmental factors, which can mimic estrogen function and thus mediate ... -
Cilia dynamics in cardiac regeneration in zebrafish (danio rerio).
(Wheaton College (Norton, Mass.), 2017)Ischemic injury in the human heart can lead to massive cell death and inelastic scar tissue formation, resulting in diminished cardiac function. In contrast, zebrafish (Danio rerio) can regenerate injured heart tissue ... -
Cilia abundance in regenerating zebrafish cardiac tissue and their potential relation to cell signaling pathways.
(Wheaton College (Norton, Mass.), 2016)Heart disease is one of the leading causes of death worldwide. After injury caused by trauma such as a myocardial infarction, human cardiac tissue is unable to heal without scaring. Damage to adult human heart tissue results ... -
The role of methylmercury on thioredoxin reductase activity in breast cancer cells.
(Wheaton College (Norton, Mass.), 2016)Metalloestrogens are small ionic metals and metalloids that activate the estrogen receptor (ER) in a manner similar to estrogen. When metalloestrogens bind to the ER, there is an increase in the expression of estrogen-related ...
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