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dc.contributor.authorHobocan, Marissa.
dc.date.accessioned2011-11-18T20:18:41Z
dc.date.available2011-11-18T20:18:41Z
dc.date.issued2011-11-18T20:18:41Z
dc.identifier.otherW Thesis 1366
dc.identifier.urihttp://hdl.handle.net/11040/23558
dc.descriptionix, 51 leaves : illustrations.
dc.descriptionBibliography: leaves 50-51.
dc.description.abstractSignificant work has been done using traditional organic solvents for catalytic asymmetric hydrogenations. Recently, there have also been reports of the successful use of alternative reaction media such as ionic liquids and water as the sole reaction solvent in the catalytic asymmetric hydrogenation of α-benzamido acrylate esters. Building off of these reports, this work looks at the plausibility of utilizing water as the sole reaction solvent in the catalytic asymmetric hydrogenation of enol ester substrates. In particular, this study employed the use of the chiral EtDuPHOS and CatASium catalysts as well as the achiral DiPFc catalyst. While the enol ester substrates, specifically the benzoates, employed in the hydrogenation reactions were successfully synthesized, the catalytic asymmetric hydrogenations in water did not yield the desired α-hydroxy acid products.en_US
dc.publisherWheaton College; Norton, Mass.
dc.subject.lcshEnantioselective catalysis.
dc.subject.lcshAsymmetric synthesis.
dc.subject.lcshAlpha hydroxy acids.
dc.subject.lcshOrganic solvents.
dc.subject.lcshIonic solutions.
dc.subject.lcshHydrogenation.
dc.subject.lcshEnols.
dc.subject.lcshEsters.
dc.titleEnantioselective hydrogenation of enol esters in water.en_US
dc.typeThesisen_US


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