Asymmetric hydrogenation of acetamido cinnamate ester in water.
Loading...
Authors
He, Shenlu.
Issue Date
2014
Type
Thesis
Language
en_US
Keywords
Undergraduate research. , Undergraduate thesis.
Alternative Title
Abstract
This research aimed to investigate the DuPHOS-Rh catalyzed asymmetric hydrogenation of acetamido cinnamate ester using water as the sole reaction solvent. The attempted synthesis of acetamido cinnamate ester was carried out using a 2-step literature procedure starting with N-acetylglycine. Six different substituted aldehydes were employed as the starting materials, all of which gave low conversion and impure acetamido cinnamate ester products. Hence, the hydrogenation reactions were not completed and further investigation is required to determine if this process is a viable method to produce protected amino acids.
Description
48 leaves : illustrations.
Bibliography: leaves 44-48.
Citation
Publisher
Wheaton College (Norton, Mass.)